Actress Amanda Seyfried has a long history of taking on particularly challenging roles, whether it be for the big screen (The Testament of Ann Lee), the stage (The Way We Get By), television (Twin Peaks: The Return), or, pertinently, streaming. In Hulu’s The Dropout, Seyfried described her role as being scary in a “specific way.” That role was Elizabeth Holmes.
In 2003, Elizabeth Holmes founded “Theranos,” a health tech company. In 2015, Holmes became one of the youngest and wealthiest self-made female billionaires in the world, after she and her company claimed to have developed advancements in blood-testing technology. These claims were proven to be false.
Currently in prison for multiple counts of fraud, Holmes returns to the news again after the release of Lance Oppenheim and Nathan Fielder’s 2026 documentary You Can See Everything. In the documentary, Fielder and a film crew were invited into Holmes and her partner Billy Evan’s home, living with them in the weeks before Holmes was to be imprisoned. For sequences in which Holmes was interviewed while in prison, cameras were prohibited, so Seyfried was recruited to the project, reprising her role in the form of reenactments.
As of writing, You Can See Everything has racked in a whopping $80 million at the box office, against a budget of a mere $7 million. This is not to mention the extremely positive reception it garnered from both critics and audiences. Reflecting on her part, Amanda Seyfried discussed her feelings with People magazine:
When you follow through with something that scares you and it comes out the other end that it’s something that’s having an impact, mostly positive impact, it always feels good because you take a risk.
For her daring and bold performance in The Dropout, Seyfried won an Emmy and a Golden Globe.
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